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PTEN regulation of ERK1/2 signaling in cancer

Since its discovery, the tumor suppressor phosphatase and tensin homolog (PTEN) has become a molecule with a wide spectrum of functions, which is typically meditated through its lipid phosphatase activity; however, PTEN also functions in a phosphatase-independent manner. It is well established that...

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Autors principals: Chetram, Mahandranauth A, Hinton, Cimona V
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503241/
https://ncbi.nlm.nih.gov/pubmed/22737980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10799893.2012.695798
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