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Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells

Here we report a microfluidics method to enrich physically deformable cells by mechanical manipulation through artificial microbarriers. Driven by hydrodynamic forces, flexible cells or cells with high metastatic propensity change shape to pass through the microbarriers and exit the separation devic...

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Detalles Bibliográficos
Main Authors: Zhang, Weijia, Kai, Kazuharu, Choi, Dong Soon, Iwamoto, Takayuki, Nguyen, Yen H., Wong, Helen, Landis, Melissa D., Ueno, Naoto T., Chang, Jenny, Qin, Lidong
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503214/
https://ncbi.nlm.nih.gov/pubmed/23112172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209893109
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