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Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells
Here we report a microfluidics method to enrich physically deformable cells by mechanical manipulation through artificial microbarriers. Driven by hydrodynamic forces, flexible cells or cells with high metastatic propensity change shape to pass through the microbarriers and exit the separation devic...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3503214/ https://ncbi.nlm.nih.gov/pubmed/23112172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209893109 |
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