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Microfluidics separation reveals the stem-cell–like deformability of tumor-initiating cells

Here we report a microfluidics method to enrich physically deformable cells by mechanical manipulation through artificial microbarriers. Driven by hydrodynamic forces, flexible cells or cells with high metastatic propensity change shape to pass through the microbarriers and exit the separation devic...

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Hlavní autoři: Zhang, Weijia, Kai, Kazuharu, Choi, Dong Soon, Iwamoto, Takayuki, Nguyen, Yen H., Wong, Helen, Landis, Melissa D., Ueno, Naoto T., Chang, Jenny, Qin, Lidong
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503214/
https://ncbi.nlm.nih.gov/pubmed/23112172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209893109
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