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Reversible online control of habitual behavior by optogenetic perturbation of medial prefrontal cortex

Habits tend to form slowly but, once formed, can have great stability. We probed these temporal characteristics of habitual behaviors by intervening optogenetically in forebrain habit circuits as rats performed well-ingrained habitual runs in a T-maze. We trained rats to perform a maze habit, confir...

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Главные авторы: Smith, Kyle S., Virkud, Arti, Deisseroth, Karl, Graybiel, Ann M.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503190/
https://ncbi.nlm.nih.gov/pubmed/23112197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216264109
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