Selection and Characterization of Autographa californica Multiple Nucleopolyhedrovirus DNA Polymerase Mutations

Autographa californica multiple nucleopolyhedrovirus (AcMNPV) DNA polymerase (DNApol) is essential for viral DNA replication. AcMNPV mutants resistant to aphidicolin, a selective inhibitor of viral DNA replication, and abacavir, an efficacious nucleoside analogue with inhibitory activity against rev...

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Autores principales: Feng, Guozhong, Thumbi, David K., de Jong, Jondavid, Hodgson, Jeffrey J., Arif, Basil M., Doucet, Daniel, Krell, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503129/
https://ncbi.nlm.nih.gov/pubmed/23035236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01507-12
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