Distinct Evolutionary Pressures Underlie Diversity in Simian Immunodeficiency Virus and Human Immunodeficiency Virus Lineages

Simian immunodeficiency virus (SIV) infection of rhesus macaques causes immune depletion and disease closely resembling human AIDS and is well recognized as the most relevant animal model for the human disease. Experimental investigations of viral pathogenesis and vaccine protection primarily involv...

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Detalhes bibliográficos
Main Authors: Fischer, Will, Apetrei, Cristian, Santiago, Mario L., Li, Yingying, Gautam, Rajeev, Pandrea, Ivona, Shaw, George M., Hahn, Beatrice H., Letvin, Norman L., Nabel, Gary J., Korber, Bette T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503124/
https://ncbi.nlm.nih.gov/pubmed/23055550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01862-12
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