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Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly

Mx1 is a GTPase that is part of the antiviral response induced by type I and type III interferons in the infected host. It inhibits influenza virus infection by blocking viral transcription and replication, but the molecular mechanism is not known. Polymerase basic protein 2 (PB2) and nucleoprotein...

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Detalhes bibliográficos
Main Authors: Verhelst, Judith, Parthoens, Eef, Schepens, Bert, Fiers, Walter, Saelens, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503048/
https://ncbi.nlm.nih.gov/pubmed/23015724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01682-12
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