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In vivo regulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: enzyme phosphorylation as an early regulatory response after intragastric administration of mevalonolactone.

Although substantial evidence supports the conclusion that 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase [mevalonate:NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34] is the major regulatory enzyme in cholesterol biosynthesis, the molecular events involved in the in vivo regulation of t...

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Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Arebalo, R E, Hardgrave, J E, Noland, B J, Scallen, T J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1980
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6256737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6429
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