Notch Activation Induces Endothelial Cell Senescence and Pro-inflammatory Response: Implication of Notch Signaling in Atherosclerosis

OBJECTIVE: Notch signaling plays pivotal roles in the pathogenesis of vascular disease. However, little is known about its role in atherosclerosis. We sought to investigate the potential involvement of the Notch signaling in atherosclerosis. METHODS: Expression of Notch pathway components in mouse a...

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Main Authors: Liu, Zhao-Jun, Tan, Yurong, Beecham, Gary W., Seo, David M., Tian, Runxia, Li, Yan, Vazquez-Padron, Roberto I., Pericak-Vance, Margaret, Vance, Jeffery M., Goldschmidt-Clermont, Pascal J., Livingstone, Alan S., Velazquez, Omaida C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502717/
https://ncbi.nlm.nih.gov/pubmed/23078884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.04.010
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