Notch Activation Induces Endothelial Cell Senescence and Pro-inflammatory Response: Implication of Notch Signaling in Atherosclerosis

OBJECTIVE: Notch signaling plays pivotal roles in the pathogenesis of vascular disease. However, little is known about its role in atherosclerosis. We sought to investigate the potential involvement of the Notch signaling in atherosclerosis. METHODS: Expression of Notch pathway components in mouse a...

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Detalhes bibliográficos
Main Authors: Liu, Zhao-Jun, Tan, Yurong, Beecham, Gary W., Seo, David M., Tian, Runxia, Li, Yan, Vazquez-Padron, Roberto I., Pericak-Vance, Margaret, Vance, Jeffery M., Goldschmidt-Clermont, Pascal J., Livingstone, Alan S., Velazquez, Omaida C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502717/
https://ncbi.nlm.nih.gov/pubmed/23078884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.04.010
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