Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons

Cognitive abilities and disorders unique to humans are thought to result from adaptively driven changes in brain transcriptomes, but little is known about the role of cis-regulatory changes affecting transcription start sites (TSS). Here, we mapped in human, chimpanzee, and macaque prefrontal cortex...

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Autores principales: Shulha, Hennady P., Crisci, Jessica L., Reshetov, Denis, Tushir, Jogender S., Cheung, Iris, Bharadwaj, Rahul, Chou, Hsin-Jung, Houston, Isaac B., Peter, Cyril J., Mitchell, Amanda C., Yao, Wei-Dong, Myers, Richard H., Chen, Jiang-fan, Preuss, Todd M., Rogaev, Evgeny I., Jensen, Jeffrey D., Weng, Zhiping, Akbarian, Schahram
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502543/
https://ncbi.nlm.nih.gov/pubmed/23185133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001427
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