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Postreplication repair and the susceptibility of Chinese hamster cells to cytotoxic and mutagenic effects of alkylating agents.

A cell variant (VR-43) resistant to the cytotoxic effect of N-methyl-N'-nitro-N-nitrosoguanidine and N-methyl-N'-nitro-N-nitrosourea was isolated from Chinese hamster V79 cells for use in studies of the relationship among cell survival, mutagenesis, and DNA repair by alkylating agents. Resistance to...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Friedman, J, Huberman, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6934532/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.6072
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