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Rapamycin has Paradoxical Effects on S6 Phosphorylation in Rats With and Without Seizures
PURPOSE: Accumulating data have demonstrated that seizures induced by kainate (KA) or pilocarpine activate the mammalian target of rapamycin (mTOR) pathway and mTOR inhibitor rapamycin can inhibit mTOR activation which subsequently has potential anti-epileptic effects. However, a preliminary study s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3502022/ https://ncbi.nlm.nih.gov/pubmed/23145776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.12013 |
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