Selective factor XIIa inhibition attenuates silent brain ischemia

OBJECTIVE: To use molecular imaging targeting coagulation pathway and inflammation to 1) better understand the pathophysiology of silent brain ischemia (SBI) and 2) monitor the effects of factor XIIa inhibition. BACKGROUND: Silent brain ischemia can be observed in patients who undergo invasive vascu...

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Bibliografiske detaljer
Main Authors: Chen, John W., Figueiredo, Jose-Luiz, Wojtkiewicz, Gregory R., Siegel, Cory, Iwamoto, Yoshiko, Kim, Dong-Eog, Nolte, Marc W., Dickneite, Gerhard, Weissleder, Ralph, Nahrendorf, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502014/
https://ncbi.nlm.nih.gov/pubmed/23153913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmg.2012.01.025
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