CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ

Hepatitis C virus infection is a major cause of chronic liver disease. CD4(+) T cells play a key role in disease outcome. However, the critical functions and associated phenotypes of intrahepatic CD4(+) T cells are not well defined. We have previously shown that CD8(+) T cells expressing the C type...

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Bibliografiska uppgifter
Huvudupphovsmän: Kang, Yu-Hoi, Seigel, Bianca, Bengsch, Bertram, Fleming, Vicki M., Billerbeck, Eva, Simmons, Ruth, Walker, Lucy, Willberg, Chris B., Barnes, Eleanor J., Bhagwanani, Anisha, Oo, Ye H., Blum, Hubert E., Adams, David H., Thimme, Robert, Klenerman, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2012
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502006/
https://ncbi.nlm.nih.gov/pubmed/23181064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00346
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