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Acid extrusion via blood–brain barrier causes brain alkalosis and seizures after neonatal asphyxia

Birth asphyxia is often associated with a high seizure burden that is predictive of poor neurodevelopmental outcome. The mechanisms underlying birth asphyxia seizures are unknown. Using an animal model of birth asphyxia based on 6-day-old rat pups, we have recently shown that the seizure burden is l...

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Hlavní autoři: Helmy, Mohamed M., Ruusuvuori, Eva, Watkins, Paul V., Voipio, Juha, Kanold, Patrick O., Kaila, Kai
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501974/
https://ncbi.nlm.nih.gov/pubmed/23125183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws257
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