Priming and inhibitory activities of RNAs for the influenza viral transcriptase do not require base pairing with the virion template RNA.

Capped ribopolymers lacking a sequence complementary to the common 3' end of the influenza virion RNA segments effectively stimulated transcription of these RNAs by the virion-associated transcriptase. Thus, stimulation of transcription results not from hydrogen bonding between the capped RNA a...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Krug, R M, Broni, B A, LaFiandra, A J, Morgan, M A, Shatkin, A J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6934519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.10.5874
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