Clinical outcome of patients with acute promyelocytic leukemia and FLT3 mutations

Acute promyelocytic leukemia (APL) represents a subset of AML with t(15;17), responsiveness to ATRA, and a favorable prognosis, yet the impact of FLT3ITD mutations over wild-type (wt)FLT3 remains unclear. We retrospectively analyzed the outcome of 26 APL patients treated at our center according to t...

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Autori principali: Singh, Harshabad, Werner, Lillian, DeAngelo, Daniel, Ballen, Karen, Amrein, Philip, Wadleigh, Martha, Neuberg, Donna, Fox, Edward, Stone, Richard, Attar, Eyal
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501727/
https://ncbi.nlm.nih.gov/pubmed/20981678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21867
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