Innate Immune Activation Enhances HIV Acquisition in Women, Diminishing the Effectiveness of Tenofovir Microbicide Gel

The antiretroviral agent, tenofovir, formulated as a vaginal microbicide gel, reduces human immunodeficiency virus (HIV) acquisition by 39% in women. This study assessed the role of preexisting immune activation in HIV acquisition in women from the CAPRISA 004 trial, to identify potential strategies...

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Detalhes bibliográficos
Main Authors: Naranbhai, Vivek, Abdool Karim, Salim S., Altfeld, Marcus, Samsunder, Natasha, Durgiah, Raveshni, Sibeko, Sengeziwe, Abdool Karim, Quarraisha, Carr, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501691/
https://ncbi.nlm.nih.gov/pubmed/22829639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis465
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