Not All G-Quadruplexes are Created Equally: An Investigation of the Structural Polymorphism of the c-Myc G-Quadruplex-Forming Sequence and its Interaction with the Porphyrin meso-Tetra(N-methyl-4-pyridyl)porphine

G-quadruplexes, DNA tertiary structures highly localized to functionally important sites within the human genome, have emerged as important new drug targets. The putative G-quadruplex-forming sequence (Pu27) in the NHE-III(1) promoter region of the c-Myc gene is of particular interest as stabilizati...

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Hlavní autoři: Le, Huy T., Miller, M. Clarke, Buscaglia, Robert, Dean, William L., Holt, Patrick A., Chaires, Jonathan B., Trent, John O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501587/
https://ncbi.nlm.nih.gov/pubmed/23108607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ob26504d
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