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Intravenous Amantadine for Freezing of Gait Resistant to Dopaminergic Therapy: A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Clinical Trial

BACKGROUND: Freezing of gait (FOG) is one of the most disabling symptoms in Parkinsonism. Open-label studies have suggested that intravenous (IV) amantadine is effective against FOG resistant to dopaminergic therapy in Parkinson's disease (PD). We evaluated the efficacy of IV amantadine on FOG...

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Detalhes bibliográficos
Main Authors: Kim, Young Eun, Yun, Ji Young, Yang, Hui June, Kim, Han-Joon, Gu, Namyi, Yoon, Seo Hyun, Cho, Joo-Youn, Jeon, Beom S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501515/
https://ncbi.nlm.nih.gov/pubmed/23185280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048890
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