Unexpected Relationships and Inbreeding in HapMap Phase III Populations

Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap pha...

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Main Authors: Stevens, Eric L., Baugher, Joseph D., Shirley, Matthew D., Frelin, Laurence P., Pevsner, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501496/
https://ncbi.nlm.nih.gov/pubmed/23185369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049575
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