γ-H2AX expression detected by immunohistochemistry correlates with prognosis in early operable non-small cell lung cancer

BACKGROUND: Phosphorylation of the H2AX histone is an early indicator of DNA double-strand breaks and of the resulting DNA damage response. In the present study, we assessed the expression and prognostic significance of γ-H2AX in a cohort of 96 patients with operable non-small cell lung carcinoma. M...

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Main Authors: Matthaios, Dimitrios, Foukas, Periklis G, Kefala, Maria, Hountis, Panagiotis, Trypsianis, Grigorios, Panayiotides, Ioannis G, Chatzaki, Ekaterini, Pantelidaki, Ekaterini, Bouros, Demosthenes, Karakitsos, Petros, Kakolyris, Stylianos
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2012
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501397/
https://ncbi.nlm.nih.gov/pubmed/23180966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36995
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