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Cellular origin and pathophysiology of chronic lymphocytic leukemia

The cellular origin of chronic lymphocytic leukemia (CLL) is still debated, although this information is critical to understanding its pathogenesis. Transcriptome analyses of CLL and the main normal B cell subsets from human blood and spleen revealed that immunoglobulin variable region (IgV) gene un...

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Detalhes bibliográficos
Main Authors: Seifert, Marc, Sellmann, Ludger, Bloehdorn, Johannes, Wein, Frederik, Stilgenbauer, Stephan, Dürig, Jan, Küppers, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501361/
https://ncbi.nlm.nih.gov/pubmed/23091163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120833
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