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Bayesian Continual Reassessment Method for Dose-Finding Trials Infusing T Cells with Limited Sample Size

We consider the design of dose-finding trials for patients with malignancies when only a limited sample size is available. The small sample size may be necessary because 1) the modality of treatment is very expensive, and/or 2) the disease under investigation is rare, requiring a lengthy period to e...

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Detalhes bibliográficos
Main Authors: Ji, Yuan, Feng, Lei, Liu, Ping, Shpall, Elizabeth J., Kebriaei, Partow, Champlin, Richard, Berry, Donald, Cooper, Laurence J.N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501341/
https://ncbi.nlm.nih.gov/pubmed/23075018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2011.582972
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