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Coupling between feedback loops in autoregulatory networks affects bistability range, open-loop gain and switching times

Biochemical regulatory networks governing diverse cellular processes such as stress-response, differentiation and cell cycle often contain coupled feedback loops. We aim to understand how features of feedback architecture, such as the number of loops, the sign of the loops and the type of their coup...

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Detalhes bibliográficos
Main Authors: Tiwari, Abhinav, Igoshin, Oleg A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501141/
https://ncbi.nlm.nih.gov/pubmed/23011599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/9/5/055003
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