Culture of Primary Bovine Chondrocytes on a Continuously Expanding Surface Inhibits Dedifferentiation

Expansion of autologous chondrocytes in vitro is used to generate adequate populations for cell-based therapies. However, standard (SD) culture methods cause loss of chondrocyte phenotype and dedifferentiation to fibroblast-like cells. Here, we use a novel surface expansion culture system in an effo...

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Autors principals: Rosenzweig, Derek H., Matmati, Mourad, Khayat, Ghazaleh, Chaudhry, Sidharth, Hinz, Boris, Quinn, Thomas M.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501116/
https://ncbi.nlm.nih.gov/pubmed/22738340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2012.0215
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