S-Nitrosylation Inhibits Pannexin 1 Channel Function

S-Nitrosylation is a post-translational modification on cysteine(s) that can regulate protein function, and pannexin 1 (Panx1) channels are present in the vasculature, a tissue rich in nitric oxide (NO) species. Therefore, we investigated whether Panx1 can be S-nitrosylated and whether this modifica...

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Hauptverfasser: Lohman, Alexander W., Weaver, Janelle L., Billaud, Marie, Sandilos, Joanna K., Griffiths, Rachael, Straub, Adam C., Penuela, Silvia, Leitinger, Norbert, Laird, Dale W., Bayliss, Douglas A., Isakson, Brant E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Membrane Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501028/
https://ncbi.nlm.nih.gov/pubmed/23033481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397976
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