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Exendin-4 as a Stimulator of Rat Insulin I Gene Promoter Activity via bZIP/CRE Interactions Sensitive to Serine/Threonine Protein Kinase Inhibitor Ro 31-8220

Signal transduction properties of exendin-4 (Ex-4) underlying its ability to stimulate rat insulin I gene promoter (RIP1) activity were assessed in the pancreatic β-cell line INS-1. Ex-4 acted via glucagon-like peptide-1 receptors to stimulate RIP1 in a glucose-dependent manner, as measured in cells...

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Bibliografiska uppgifter
Huvudupphovsmän: CHEPURNY, OLEG G., HUSSAIN, MEHBOOB A., HOLZ, GEORGE G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2002
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500996/
https://ncbi.nlm.nih.gov/pubmed/12021195
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