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Peptide inhibitor of morphine- and beta-endorphin-induced analgesia.

The synthetic beta-endorphin analogs with the omission of the NH2-terminal [Met]enkephalin segment [beta-endorphin-(6-31) and beta-endorphin-(20-31)] are shown to inhibit morphine- or beta-endorphin-induced analgesia in mice by the tail-flick test, whereas the synthetic NH2-terminal pentadecapeptide...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lee, N M, Friedman, H J, Leybin, L, Cho, T M, Loh, H H, Li, C H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6254086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5525
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