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Equivocal p16 Immunostaining in Squamous Cell Carcinoma of the Head and Neck: Staining Patterns are Suggestive of HPV Status

p16 immunohistochemistry (IHC) is commonly used as a surrogate marker for human papillomavirus (HPV) detection in squamous cell carcinomas of the head and neck (SCCHN). However, the HPV status of tumors not staining strongly for p16 is difficult to interpret and may require the use of PCR, not avail...

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Bibliografiske detaljer
Main Authors: Chen, Zhongchuan Will, Weinreb, Ilan, Kamel-Reid, Suzanne, Perez-Ordoñez, Bayardo
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500888/
https://ncbi.nlm.nih.gov/pubmed/22801997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-012-0382-3
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