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The conserved kinase SRPK regulates karyosome formation and spindle microtubule assembly in Drosophila oocytes

In Drosophila oocytes, after the completion of recombination, meiotic chromosomes form a compact cluster called the karyosome within the nucleus, and later assemble spindle microtubules without centrosomes. Although these oocyte-specific phenomena are also observed in humans, their molecular basis i...

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Autors principals: Loh, Benjamin J., Cullen, C. Fiona, Vogt, Nina, Ohkura, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500864/
https://ncbi.nlm.nih.gov/pubmed/22854045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.107979
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