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In the Newborn Hippocampus, Neurotrophin-Dependent Survival Requires Spontaneous Activity and Integrin Signaling

The nervous system develops through a program that first produces neurons in excess and then eliminates as many as half in a specific period of early postnatal life. Neurotrophins are widely thought to regulate neuronal survival, but this role has not been clearly defined in the CNS. Here we show th...

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Detalhes bibliográficos
Main Authors: Murase, Sachiko, Owens, David F., McKay, Ronald D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500851/
https://ncbi.nlm.nih.gov/pubmed/21613492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0202-11.2011
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