Syngeneic tumor cells can induce alloreactive T killer cells: a biological role for transplantation antigens.

A chemically induced sarcoma of BALB/c (H-2d) mice, MCG4, is shown to induce in BALB/c lymphocytes a primary anti-tumor cytolytic T lymphocyte (CTL) reaction in vitro. The anti-tumor CTL showed tumor specificity but reacted also with normal cells expressing distinct H-2 alloantigens. The CTL respons...

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Bibliographic Details
Main Authors: Schirrmacher, V, Hübsch, D, Garrido, F
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC350068/
https://ncbi.nlm.nih.gov/pubmed/6449011
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