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Multimodality Imaging of Breast Cancer Experimental Lung Metastasis with Bioluminescence and a Monoclonal Antibody Dual-Labeled with (89)Zr and IRDye 800CW

Metastatic breast cancer is incurable. The goal of this study was to develop a positron emission tomography (PET)/near-infrared fluorescent (NIRF) probe for imaging of CD105 expression in breast cancer experimental lung metastasis. TRC105, a chimeric anti-CD105 antibody, was dual-labeled with a NIRF...

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Detalhes bibliográficos
Main Authors: Hong, Hao, Zhang, Yin, Severin, Gregory W., Yang, Yunan, Engle, Jonathan W., Niu, Gang, Nickles, Robert J., Chen, Xiaoyuan, Leigh, Bryan R., Barnhart, Todd E., Cai, Weibo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500677/
https://ncbi.nlm.nih.gov/pubmed/22784250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300277f
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