Circulating Levels of Soluble KIT Serve as a Biomarker for Clinical Outcome in Gastrointestinal Stromal Tumor Patients Receiving Sunitinib following Imatinib Failure

PURPOSE: To evaluate changes in circulating levels of soluble KIT (sKIT) extracellular domain as a potential biomarker for clinical outcome in gastrointestinal stromal tumor patients treated with the multitargeted tyrosine kinase inhibitor sunitinib following imatinib failure in a previously reporte...

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Main Authors: DePrimo, Samuel E., Huang, Xin, Blackstein, Martin E., Garrett, Christopher R., Harmon, Charles S., Schöffski, Patrick, Shah, Manisha H., Verweij, Jaap, Baum, Charles M., Demetri, George D.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500590/
https://ncbi.nlm.nih.gov/pubmed/19737953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2480
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