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Sox2 in the dermal papilla niche controls hair growth by fine-tuning Bmp signaling in differentiating hair shaft progenitors

How dermal papilla (DP) niche cells regulate hair follicle progenitors to control hair growth remains unclear. Using Tbx18(Cre) to target embryonic DP precursors, we ablate the transcription factor Sox2 early and efficiently, resulting in diminished hair shaft outgrowth. We find that DP niche expres...

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Detalhes bibliográficos
Main Authors: Clavel, Carlos, Grisanti, Laura, Zemla, Roland, Rezza, Amelie, Barros, Rita, Sennett, Rachel, Mazloom, Amin, Chung, Chi-Yeh, Cai, Xiaoqiang, Cai, Chen-Leng, Pevny, Larysa, Nicolis, Silvia, Ma’ayan, Avi, Rendl, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500526/
https://ncbi.nlm.nih.gov/pubmed/23153495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.10.013
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