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Epigenetic inactivation of endothelin-2 (ET-2) and ET-3 in colon cancer

Endothelin-1 (ET-1) and its receptors are overexpressed in human cancers, but much less is known about the roles of ET-2 and ET-3 in cancer etiology. We sought to examine human and rat colon tumors for dysregulation of ET-2 and ET3 expression, and determine the underlying mechanisms. Human primary c...

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Detalhes bibliográficos
Main Authors: Wang, Rong, Löhr, Christiane V., Fischer, Kay, Dashwood, W. Mohaiza, Greenwood, Jeffrey A., Ho, Emily, Williams, David E., Ashktorab, Hassan, Dashwood, Michael R., Dashwood, Roderick H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500448/
https://ncbi.nlm.nih.gov/pubmed/22865632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27762
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