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Prohibitin attenuates colitis-associated tumorigenesis in mice by modulating p53 and STAT3 apoptotic responses

Although inflammatory bowel disease is associated with higher risk of colorectal cancer, the precise pathogenic mechanisms underlying this association are not completely understood. Prohibitin 1 (PHB), a protein implicated in the regulation of proliferation, apoptosis, and transcription, is decrease...

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Detaylı Bibliyografya
Asıl Yazarlar: Kathiria, Arwa S., Neumann, William L., Rhees, Jennifer, Hotchkiss, Erin, Cheng, Yulan, Genta, Robert M., Meltzer, Stephen J., Souza, Rhonda F., Theiss, Arianne L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500430/
https://ncbi.nlm.nih.gov/pubmed/22869582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0603
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