Selective effects of phorbol 12-myristate 13-acetate on myofibrils and 10-nm filaments.

Phorbol 12-myristate 13-acetate (PMA) has a prompt and selective catabolic effect on striated myofibrils in postmitotic myotubes. Fluorescein-labeled antibodies against light meromyosin were used to follow the effects of PMA on the muscle-specific myosin in myofibrils. The response of actin filament...

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Bibliographic Details
Main Authors: Croop, J, Toyama, Y, Dlugosz, A A, Holtzer, H
Format: Artigo
Language:Inglês
Published: 1980
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC350040/
https://ncbi.nlm.nih.gov/pubmed/7001476
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