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Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

Three different human tumor lines in culture, a rhabdomyosarcoma, a bronchogenic carcinoma and a metastatic melanoma, release proteins (transforming growth factors, TGFs) into the medium that confer the transformed phenotype on untransformed fibroblasts. These proteins are acid and heat-stable; prod...

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Dettagli Bibliografici
Autori principali: Todaro, G J, Fryling, C, De Larco, J E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC350037/
https://ncbi.nlm.nih.gov/pubmed/6254071
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