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New Alternately Colored FRET Sensors for Simultaneous Monitoring of Zn(2+) in Multiple Cellular Locations

Genetically encoded sensors based on fluorescence resonance energy transfer (FRET) are powerful tools for reporting on ions, molecules and biochemical reactions in living cells. Here we describe the development of new sensors for Zn(2+)based on alternate FRET-pairs that do not involve the traditiona...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miranda, Jose G., Weaver, Amanda L., Qin, Yan, Park, J. Genevieve, Stoddard, Caitlin I., Lin, Michael Z., Palmer, Amy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500285/
https://ncbi.nlm.nih.gov/pubmed/23173058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049371
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