Osteoclasts in Multiple Myeloma Are Derived from Gr-1+CD11b+Myeloid-Derived Suppressor Cells

Osteoclasts play a key role in the development of cancer-associated osteolytic lesions. The number and activity of osteoclasts are often enhanced by tumors. However, the origin of osteoclasts is unknown. Myeloid-derived suppressor cells (MDSCs) are one of the pre-metastatic niche components that are...

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Библиографические подробности
Главные авторы: Zhuang, Junling, Zhang, Jianghong, Lwin, Seint T., Edwards, James R., Edwards, Claire M., Mundy, Gregory R., Yang, Xiangli
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500251/
https://ncbi.nlm.nih.gov/pubmed/23173040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048871
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