Different fatty acid metabolism effects of (−)-Epigallocatechin-3-Gallate and C75 in Adenocarcinoma lung cancer

BACKGROUND: Fatty acid synthase (FASN) is overexpressed and hyperactivated in several human carcinomas, including lung cancer. We characterize and compare the anti-cancer effects of the FASN inhibitors C75 and (−)-epigallocatechin-3-gallate (EGCG) in a lung cancer model. METHODS: We evaluated in vit...

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Hauptverfasser: Relat, Joana, Blancafort, Adriana, Oliveras, Glòria, Cufí, Sílvia, Haro, Diego, Marrero, Pedro F, Puig, Teresa
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500220/
https://ncbi.nlm.nih.gov/pubmed/22769244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-280
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