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Communication between catalytic subunits in hybrid aspartate transcarbamoylase molecules: effect of ligand binding to active chains on the conformation of unliganded, inactive chains.

In the regulatory enzyme aspartate transcarbamoylase (aspartate carbamoyltransferase; carbamoylphosphate:L-aspartate carbamoyltransferase, EC 2.1.3.2) of Escherichia coli, the six catalytic polypeptide chains are arranged as two distinct catalytic trimers "crosslinked" by three regulatory...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Yang, Y R, Schachman, H K
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1980
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933552/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.9.5187
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