Screening of human pluripotent stem cells using CGH and FISH reveals low-grade mosaic aneuploidy and a recurrent amplification of chromosome 1q

Pluripotency and proliferative capacity of human embryonic stem cells (hESCs) make them a promising source for basic and applied research as well as in therapeutic medicine. The introduction of human induced pluripotent cells (hiPSCs) holds great promise for patient-tailored regenerative medicine th...

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Autori principali: Dekel-Naftali, Michal, Aviram-Goldring, Ayala, Litmanovitch, Talia, Shamash, Jana, Reznik-Wolf, Haike, Laevsky, Ilana, Amit, Michal, Itskovitz-Eldor, Joseph, Yung, Yuval, Hourvitz, Ariel, Schiff, Eyal, Rienstein, Shlomit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499752/
https://ncbi.nlm.nih.gov/pubmed/22713809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.128
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