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A Meta-analysis of Factors Impacting Detection of Antidepressant Efficacy in Clinical Trials: The Importance of Academic Sites

Variability in placebo response greatly complicates the design, conduct, and interpretation of clinical trials of antidepressant medications. To identify factors that impact detection of antidepressant–placebo differences, we conducted a meta-analysis of all relevant phase II–IV clinical trials for...

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Autori principali: Dunlop, Boadie W, Thase, Michael E, Wun, Chuan-Chuan, Fayyad, Rana, Guico-Pabia, Christine J, Musgnung, Jeff, Ninan, Philip T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499718/
https://ncbi.nlm.nih.gov/pubmed/22910458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.153
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