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The Impact of Gabapentin Administration on Brain GABA and Glutamate Concentrations: A 7T (1)H-MRS Study

Gamma-aminobutyric acid (GABA) and glutamate are implicated in numerous neuropsychiatric and substance abuse conditions, but their spectral overlap with other resonances makes them a challenge to quantify in humans. Gabapentin, marketed for the treatment of seizures and neuropathic pain, has been sh...

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Main Authors: Cai, Kejia, Nanga, Ravi PR, Lamprou, Lisa, Schinstine, Claudia, Elliott, Mark, Hariharan, Hari, Reddy, Ravinder, Epperson, C Neill
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499716/
https://ncbi.nlm.nih.gov/pubmed/22871916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.142
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