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Purine nucleosides: endogenous neuroprotectants in hypoxic brain

ABSTRACT: Even a short blockade of oxygen flow in brain may lead to the inhibition of oxidative phosphorylation and depletion of cellular ATP, which results in profound deficiencies in cellular function. Following ischemia, dying, injured, and hypoxic cells release soluble purine-nucleotide and -nuc...

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Detalhes bibliográficos
Main Authors: Thauerer, Bettina, zur Nedden, Stephanie, Baier-Bitterlich, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499684/
https://ncbi.nlm.nih.gov/pubmed/22335456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07692.x
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